When it comes to diagnosing and managing complex conditions like lactic acidosis, precision is critical—not just for patient outcomes, but for the financial stability of your practice. Are you confident that your documentation and coding align with current medical billing standards? Even a minor mistake in coding, such as misapplying the Lactic Acidosis ICD-10 code, can result in claim denials, delayed reimbursements, and increased administrative workload. Ensuring accuracy in coding is essential to maintain compliance and optimize revenue cycle performance.
In this guide, we’ll empower healthcare providers like you with the insights and tools you need to navigate the ICD-10 coding for lactic acidosis, ensuring your practice thrives while delivering the highest standard of care to your patients.
What is Lactic Acidosis?
Lactic acidosis is a serious condition that occurs when there is too much lactic acid in the bloodstream. Normally, lactic acid is produced when the body breaks down glucose for energy in the absence of oxygen.
However, when something goes wrong with the body’s metabolism or oxygen supply, lactic acid can build up to dangerous levels. This condition can arise from a variety of underlying causes, including sepsis, severe dehydration, or conditions like diabetic ketoacidosis.
It’s crucial for healthcare providers to diagnose lactic acidosis early, as it can quickly lead to severe complications if left untreated.
Understanding the ICD-10 Codes for Lactic Acidosis
The ICD-10 system helps categorize and document diagnoses for better clarity and more accurate healthcare billing. When it comes to lactic acidosis, there are several relevant ICD-10 codes that healthcare providers should know.
Below, we break down the key codes for lactic acidosis and related conditions, highlighting when each one should be used.

E87.2 – Acidosis (General Code for Acidosis)
E87.2 is the general ICD-10 code used for acidosis. This code can be applied to a wide range of acid-base imbalances, including lactic acidosis. It is a broad category and does not specify the exact cause of acidosis.
Providers should use this code when acidosis is diagnosed but the underlying cause (e.g., lactic acidosis, diabetic ketoacidosis) has not been determined yet.
Tip: E87.2 is ideal when a definitive cause of acidosis hasn’t been established or when you are treating a patient with more generalized metabolic acidosis.
E87.21 – Acute Metabolic Acidosis
E87.21 is the correct code when a patient presents with acute metabolic acidosis. This condition often develops quickly, and lactic acidosis is a common cause. Acute metabolic acidosis can be associated with many serious conditions, including sepsis, diabetic ketoacidosis, and, of course, lactic acidosis. Identifying this form of acidosis early is essential for rapid treatment and recovery.
Tip: If the patient is in an acute phase, with rapid onset of symptoms and a suspected buildup of lactate in the blood, E87.21 is the most accurate code to use.
E87.20 – Non-Specific Acidosis
Sometimes, a diagnosis of acidosis is made, but the exact type or cause of the condition remains unclear. In this case, E87.20 is used. This code serves as a general placeholder for acidosis when further tests or evaluations have not yet determined whether the acidosis is metabolic, respiratory, or mixed.
Tip: Use E87.20 when the diagnosis of acidosis is confirmed, but the specific cause is still under investigation or if it is unclear whether lactic acidosis is involved.
R74.0 – Elevated LDH and Transaminase Levels
Elevated levels of lactate dehydrogenase (LDH) and transaminases can be indicative of various medical conditions, including lactic acidosis. The R74.0 code is used when there is a nonspecific elevation of these enzymes, but the exact cause of the elevation isn’t immediately clear.
Tip: R74.0 is helpful for tracking enzyme levels when a clinician suspects lactic acidosis but needs to investigate further to confirm the diagnosis.
E87.4 – Mixed Acid-Base Disorders
In some cases, patients may present with mixed acid-base disorders, where different types of acid-base imbalances coexist. This may include lactic acidosis in conjunction with other forms of acidosis or alkalosis. The code E87.4 is used to classify such mixed conditions.
Tip: Use E87.4 when a patient shows signs of both lactic acidosis and another form of metabolic disturbance. This will help paint an accurate picture of the patient’s clinical status for both treatment and billing purposes.
When to Use Each Code?
Choosing the correct ICD-10 code is critical not only for accurate diagnosis but also for smooth billing processes. Let’s break down some common clinical scenarios to show when to use each code.
Example 1: Acute Lactic Acidosis from Sepsis
A patient is admitted with severe sepsis, and tests confirm they have acute metabolic acidosis with elevated lactate levels. In this case, E87.21 (Acute Metabolic Acidosis) would be the correct code. This scenario clearly points to lactic acidosis as the cause of the metabolic disturbance.
Example 2: General Acidosis with Unclear Cause
A patient presents with signs of acidosis, but there are no clear indications of lactic acidosis or other causes. Blood tests are pending. In this case, E87.20 would be used, as the acidosis is identified, but the cause is still under investigation.
Example 3: Elevated Enzyme Levels without Clear Cause
A patient has elevated LDH and transaminase levels, but no definitive diagnosis has been made yet. The code R74.0 would be appropriate here to indicate elevated enzyme levels, with further tests needed to determine if lactic acidosis is present.
Example 4: Mixed Acid-Base Disorders
A patient presents with a combination of lactic acidosis and respiratory acidosis, likely due to both a metabolic and a respiratory issue. E87.4 would be used to describe this mixed acid-base disorder.
Why Accurate Billing for Lactic Acidosis Matters?
Accurate ICD-10 coding does more than ensure correct diagnosis—it is essential for ensuring timely and correct reimbursement for the services provided. Errors in coding can result in claim denials, delayed payments, and extra administrative work for your practice.
By accurately coding for lactic acidosis and related conditions, healthcare providers ensure that patients get the right treatments while also keeping billing processes smooth and efficient. Healthcare providers should also be aware that proper documentation is a critical factor when it comes to insurance reimbursements.
A claim without accurate and clear coding for lactic acidosis may result in delays or denials, making it harder to cover the costs of care. This is especially important when dealing with complex metabolic imbalances that require timely intervention.
In Closing
Accurate coding and documentation are essential for both patient care and practice efficiency. Lactic acidosis, while potentially life-threatening, can be effectively managed when diagnosed and treated promptly. By understanding and properly using the ICD-10 codes for lactic acidosis, healthcare providers and billing professionals ensure that patients receive the best care while avoiding costly errors in billing. Take the time to review your coding practices, and remember—accuracy is key to smooth operations and proper reimbursement.